Centre for Translational Cancer Research

Publications

2020

Apurv Kulkarni, Devaki A Kelkar, L S Shashidhara, C B Koppiker, Madhura Kulkarni*. Meta-analysis of prevalence and clinical features at presentation of TNBC in Indian Cohort. JCO Glob Oncol 2020 Jul;6:1052-1062. https://ascopubs.org/doi/full/10.1200/GO.20.00054

 

Nagarkar, S., Wasnik, R., Govada, P., Cohen, S.M. and Shashidhara, L.S. (2020). Promoter proximal pausing limits Yki-induced tumorous growth in Drosophila. Genetics (early online) https://doi.org/10.1534/genetics.120.303419.

 

Groth, C., Vaid, P., Khatpe, A., Prashali, N., Ahiya, A., Andrejeva, D., Chakladar, M., Nagarkar, S., Paul, R., Kelkar, D., Eichenlaub, T., Herranz, H., Sridhar, T.S., Cohen, S.M., and Shashidhara, L.S. (2020) Genome-wide RNAi screen for context-dependent tumor suppressors identified using in vivo models for neoplasia in Drosophila. G3: Genes, Genomes, Genetics (early online) https://doi.org/10.1534/g3.120.401545.

 

Nandini A. Sahasrabuddhe, Aruna Korlimarla, Madhura Kulkarni, Vinay Kusuma, Jyothi S. Prabhu, Santosh Dixit, Chetan Deshmukh, T. S. Sridhar, Aditya Phatak, C B Koppiker. “NGS-based profiling of key cancer genes in Indian TNBC patients reinforces molecular heterogeneity of TNBCs.” (Under revision at Indian Journal of Cancer)

 

Pooja Vaid, Aditi Khatpe, Rutvi Shah, Ruhi Reddy, Devaki Kelkar, Anirudha Puntambekar, Chaitanyanand Koppiker, LS Shashidhara, Madhura Kulkarni* Evaluation of Tumor Infiltrating Lymphocytes (TILs) as a prognostic and predictive marker in Indian breast cancer. medRxiv doi: https://doi.org/10.1101/2020.08.19.20177865

 

Chakladar M, Nair, MG., Prabhu, JS., Sridhar, TS., Kelkar, D., Kulkarni, M., Shashidhara, LS (202). PTPN11 / SHP2 negatively regulates growth in breast epithelial cells: implications on tumorigenesis. BioRxiv. doi: https://doi.org/10.1101/2020.07.30.228445.

2019

Chaitanyanand B. Koppiker, Chintamani, Santosh Dixit. (2019) Oncoplastic Breast Surgery in India : Thinking Globally , Acting Locally. Indian Journal of Surgery. 81(2): 103-110. https://doi.org/10.1007/s12262-019-01890-8

 

Mrc1 and Tof1 prevent fragility and instability at long CAG repeats by their fork stabilizing function. Gellon L, Kaushal S, Cebrián J, Lahiri M, Mirkin SM, Freudenreich CH.Nucleic Acids Res. 2019 Jan 25;47(2):794-805. doi: 10.1093/nar/gky1195.

 

Koppiker, C.B., Noor, A.U., Dixit, S. et al. (2019). Implant-Based Breast Reconstruction with Autologous Lower Dermal Sling and Radiation Therapy Outcomes. Indian J Surg.   https://doi.org/10.1007/s12262-018-1856-7

 

Koppiker C. B., Noor A. U., Dixit S., Busheri L., Sharan G., Dhar U., Allampati H. K., Nare S. (2019). Extreme Oncoplastic Surgery for Multifocal/Multicentric and Locally Advanced Breast Cancer. Int J Breast Cancer. 2019:4262589. doi: 10.1155/2019/4262589

 

Groth, C., Vaid, P., Khatpe, A., Prashali, N., Ahiya, A., Andrejeva, D., Chakladar, M., Nagarkar, S., Paul, R., Eichenlaub, T., Herranz, H., Sridhar, T.S., Cohen, S.M., and Shashidhara, L.S. (2019) Genome-wide RNAi screen for context-dependent tumor suppressors identified using in vivo models for neoplasia in Drosophila. BioRxiv preprint: https://doi.org/10.1101/643221

 

Varghese, B., Deshpande, P., Dixit, S., Koppiker, C. B., and Jalnapurkar N. (2019) Primary Angiosarcoma Of the Breast: A Case Report. Radiology Case. 13:15-25. doi: 10.3941/jrcr.v13i2.3449

2018

Rekha Jakhar, Monique N.H. Luijten, Alex X.F. Wong, Bing Cheng, Suat Neo, Bijin Au, Madhura Kulkarni, Kah J. Lim, Jiamila Maimaiti, Han C. Chong, Elaine H. Lim, Tee B. K. Tan, Kong W. Ong, Yirong Sim, Jill S. L. Wong, James B.K. Khoo, Juliana T.S. Ho, Ke Guo1, Boon T. Chua, Indrajit Sinha, Xiaomeng Wang John E. Connolly, Jayantha Gunaratne and Karen C. Crasta. Autophagy governs pro-tumourigenic effects of mitotic slippage-1 induced senescence. Molecular Cancer Research 16:1625-1640

 

Qianqian He, Bijin Au, Madhura Kulkarni, Yang Shen, Kah J. Lim, Jiamila Maimaiti, Cheng Kit Wong, Giulia Rancati, Indrajit Sinha, Zhiyan Fu, Xiaomeng Wang, John E. Connolly and Karen C. Crasta. Chromosomal instability-induced senescence potentiates cell non-autonomous tumorigenic effects. Oncogenesis 7:62.

 

Madhura Kulkarni, Tuan Zea Tan, Nurfarhanah Sulaiman, John Lamar, Prashali Bansal, Jianzhou Cui, Yiting Qiao, Yoshiaki Ito. RUNX1 and RUNX3 protect against YAP-mediated EMT, stem-ness and shorter survival outcomes in breast cancer. Oncotarget 2018; 9:14175-14192

 

De las Heras, J.M., Garcia-Cortes, C., Foronda, D., Pastor-Pareja, J.C., Shashidhara, L.S. and Sanchez-Herrero, E. (2018). The Drosophila Hox gene Ultrabithorax controls appendage shape by regulating extracellular matrix dynamics. Development (doi: 10.1242/dev.161844).

 

Vaidehi Krishnan, Yu Lin Chong, Tuan Zea Tan, Madhura Kulkarni, Muhammad Bakhait Bin Rahmat, Lavina Sierra Tay, Haresh Sankar, Doorgesh Jokhun, Amudha Ganesan, Linda Shyue Huey Chuang, Dominic Voon, G V Shivashankar, Jean Paul Thiery, and Yoshiaki Ito. TGF-β promotes genomic instability upon RUNX3 deficiency. Cancer Research  2018 Jan 1;78(1):88-10

2017

Krishnan Lakshmi, Bapat Anita, Sakhilkar Reshma, Raje Sachin, Gaikwad Amol, Busheri Laleh, Dixit Santosh, Koppiker C B (2017) Telemedicine-Based Community Screening of Cervical Cancer. Indian Journal of Public Health Research & Development. 8(4)547-553. DOI: 10.5958/0976-5506.2017.00397.7

 

Palvai, S*., Libi Anandi*; Sarkar, S.; Augustus, M.; Roy.; Lahiri, M.# and Basu, S.# (2017) Drug-Triggered Self-Assembly of Linear Polymer into Nanoparticles for Simultaneous Delivery of Hydrophobic and Hydrophilic Drugs in Breast Cancer Cells. ACS Omega 2:8730 - 40. * equal contribution; # corresponding authors

 

Gandhi Theerthagiri, Madhura Kulkani, Ho Sze Yuan, Adrian Boey, Edmond Wei Min Chua, Veluchamy A. Barathi, Tom J. Carney, Xiaomeng Wang and Wanjin Hong. (2017) Cavin-2 regulates the activity and stability of eNOS in angiogenesis. J Bio Chem.292:17760-17776.

 

Baptist, J., Dixit, S., Busheri, L., Krishnan, L., Alhat, R., Verghese, B., and Koppiker, C. (2017) Evaluating the Performance of an Advanced Breast Cancer Diagnosis Unit in India. Indian Journal of Public Health Research & Development 8: 598-604.

 

Shukla, J.P., Deshpande, G. and Shashidhara, L.S. (2017). Ataxin-2 binding protein 1 is a context-specific positive regulator of Notch signaling during neurogenesis in Drosophila melanogaster. Development (doi: 10.1242/dev.140657)

 

Nare, S., Dixit, S., Verghese, B., Krishnan, L., Busheri, L., Deshmukh, C., and Koppiker, C. (2017) Breast Cancer Biobank: A Novel Resource for Translational Research. Indian Journal of Public Health Research & Development 8:1031-1040.

 

Jadhav, M., Krishnan, L., Dixit, S., Jadhav, S., Gaikwad, A., Busheri, L., Verghese, B., Patil, A., Koppiker, C. (2017) Performance of CBE and Mammography for Breast Cancer Screening in Indian Setup. Indian Journal of Public Health Research & Development. 8:700-707.

 

Anandi, L., Chakravarty*, V.; Ashiq, KA.*, Bodakuntla, S. and Lahiri, M. (2017) DNA-PK plays a central role in transformation of breast epithelial cells following alkylation damage. Journal of Cell Sciences 130:3749-3763; DOI: 10.1242/jcs.203034.  (*equal contribution)